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ChemInform Abstract: Synthesis of Purine and Pyrimidine 3′-Amino-3′-deoxy- and 3′-Amino-2′, 3′-dideoxyxylonucleosides.

✍ Scribed by L. F. GARCIA-ALLES; J. MAGDALENA; V. GOTOR


Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
28
Category
Article
ISSN
0931-7597

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Synthesis of (-)-3-Amino-3-deoxyquinic Acid. -The title acid (X) is prepared in nine steps from quinic acid (I) in 14% overall yield. Its importance for the biosynthesis of 3-amino-5-hydroxybenzoic acid, the precursor of mC 7 N-units in ansamycin and mitomycin antibiotics is discussed. -