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ChemInform Abstract: Synthesis of Polysubstituted Dihydropyridines by Four-Component Reactions of Aromatic Aldehydes, Malononitrile, Arylamines, and Acetylenedicarboxylate.

✍ Scribed by Jing Sun; Er-Yan Xia; Qun Wu; Chao-Guo Yan

Publisher
John Wiley and Sons
Year
2010
Weight
38 KB
Volume
41
Category
Article
ISSN
0931-7597

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Selective Synthesis of Fused 1,4- and 1,
Selective Synthesis of Fused 1,4- and 1,2-Dihydropyridines by Domino Reactions of Arylamines, Acetylenedicarboxylate, Aldehydes, and Cyclic 1,3-Diketones
✍ Jing Sun; Yan Sun; Hong Gao; Chao-Guo Yan πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 565 KB

## Abstract A practical procedure for the preparation of fused 1,4‐dihydropyridines was developed through the domino four‐component reactions of arylamines, acetylenedicarboxylate, aromatic aldehydes, and cyclic 1,3‐diketones in acetic acid. Unusual fused 1,2‐dihydropyridines can also be efficientl