Synthesis of piperidine analogs of 1-(3-
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Stanislav RΓ‘dl; Petr HezkΓ½; Jan Taimr; Jan ProΕ‘ka; Ivan KrejΔΓ
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Article
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1999
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Journal of Heterocyclic Chemistry
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English
β 469 KB
## Abstract Synthesis of arylpiperideines 3aβ3d and arylpiperidines 4aβ4d as analogs of a well known serotonin ligand 1β(3βchlorophenyl)piperazine is reported. Starting aryllithium derivatives were treated with 1βmethylβpiperdinβ4βone to provide the corresponding hydroxy derivatives 6a and 6b. __N_