ChemInform Abstract: Synthesis of Phosphoramide Mustard Analogues of Daunomycin and Carminomycin.
β Scribed by A. CSORVASI; K. E. KOEVER; M. M. MENYHART; F. SZTARICSKAI; Y. V. DOBRYNIN; T. G. NIKOLAEVA
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 32 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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## Abstract The cyclophosphamide metabolite phosphoramide mustard (PM) was synthesized with isotopic enrichment at each nitrogen and oxygen site. Sequential reaction of __N,N__βbis(2βchloroethyl)phosphoramidic dichloride [Cl~2~P(__O__)N(CH~2~CH~2~Cl)~2~] with benzyl alcohol and ammonia gave __N,N__
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