Aziridine 2-Carboxylate Ester Mediated Asymmetric Synthesis of α-Alkyl β-Amino Acids. -Highly stereoselective reductive ring opening of the N-tosylaziridines (II) with LiAlH4 followed by oxidation of the syn-amino alcohols (III) provides an efficient entry to the asymmetric synthesis of αmethyl β-am
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ChemInform Abstract: Synthesis of Optically Active 2-Alkyl-3,4-iminobutanoic Acids. β-Amino Acids Containing an Aziridine Heterocycle.
✍ Scribed by Jeong-il Park; Guan Rong Tian; Dong H. Kim
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 34 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0931-7597
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