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ChemInform Abstract: Synthesis of Oligodeoxynucleotides Containing 6-N-((13C)Methyl)adenine and 2-N-((13C)Methyl)guanine

✍ Scribed by M. HOFMANN; M. ACEDO; P. FAGAN; D. WEMMER; R. ERITJA; A. R. DIAZ


Publisher
John Wiley and Sons
Year
2010
Weight
25 KB
Volume
28
Category
Article
ISSN
0931-7597

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✦ Synopsis


Synthesis

of Oligodeoxynucleotides Containing 6-N-((13C)Methyl)adenine and 2-N-((13C)Methyl)guanine -The title compounds are prepared for NMR studies to investigate DNA-protein interactions.


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Synthesis of [3-D3]-, [3-13C]-, and [1,2
✍ Claude Boullais; Christelle Rannou; Emmanuel RΓ©veillΓ¨re; Charles Mioskowski πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 242 KB πŸ‘ 1 views

Three selectively labeled propynes were prepared either with deuterium or carbon-13 at position 3 and doubly labeled with carbon-13 at positions 1 and 2 by an alkylation reaction from the corresponding labeled or unlabeled monolithio acetylides and dimethylsulfates. Their lithiation with nBuLi gave