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ChemInform Abstract: Synthesis of Novel γ-Aminobutyric Acid (GABA) Uptake Inhibitors. Part 5. Preparation and Structure—Activity Studies of Tricyclic Analogues of Known GABA Uptake Inhibitors.

✍ Scribed by Knud Erik Andersen; Jan L. Soerensen; Jesper Lau; Behrend F. Lundt; Hans Petersen; Per O. Huusfeldt; Peter D. Suzdak; Michael D. B. Swedberg


Publisher
John Wiley and Sons
Year
2010
Weight
34 KB
Volume
32
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Synthesis of 4,4-Bi
✍ N. IQBAL; Z.-Y. WEI; G. B. BAKER; E. E. KNAUS 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 37 KB 👁 1 views

Synthesis of 4,4-Bis(2-methylphenyl)-3-butenyl (and butyl) Analogues of 4-Phenyl-1,4,-and 6-Phenyl-1,6-dihydropyridine-3-carboxylic Acids and Their Evaluation as Neuronal GABA-Uptake Inhibitors. -All attempts to hydrolyze the esters (VIII) and (IX) to a carboxyl group result in decomposition product