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ChemInform Abstract: Synthesis of Novel L-Series 2′,3′-Dideoxy-3′-hydroxymethyl Nucleosides and a Convenient Method for the Separation of Nucleoside Anomers.

✍ Scribed by J. H. M. GOULD; J. MANN


Publisher
John Wiley and Sons
Year
2010
Weight
34 KB
Volume
28
Category
Article
ISSN
0931-7597

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Synthesis and Biological Evaluation of a Series of 2'-Fluorinated-2',3'-dideoxy-2',3'-didehydro-(L)-nucleosides. -A general method for the synthesis of both the cis-and trans-2'-vinylfluoro containing nucleosides is presented. Among the nucleosides prepared compound (XI) displays the best biologica