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ChemInform Abstract: Synthesis of Nodulisporic Acid 2′′-Oxazoles and 2′′-Thiazoles.

✍ Scribed by Steven L. Colletti; et al. et al.

Publisher
John Wiley and Sons
Year
2010
Weight
26 KB
Volume
33
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

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Synthesis of 2-Oxiranyl and Aziridinyl Thiazoles. -Lithiation of thiazoles (I) and (XVI) and subsequent reaction of the resulting 2-lithiothiazole intermediates with α-halogenocarbonyl compounds or α-halogenoimines provides a convenient access to 2-oxiranyl and aziridinyl thiazoles. However, no suc