ChemInform Abstract: Synthesis of New Chiral Peptide Nucleic Acid (PNA) Monomers by a Simplified Reductive Amination Method.
β Scribed by Bogdan Falkiewicz; Katarzyna Kowalska; Aleksandra S. Kolodziejczyk; Kazimierz Wisniewski; Leszek Lankiewicz
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 31 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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Synthesis of a Monocharged Peptide Nucleic Acid (PNA) Analogue and Its Recognition as Substrate by DNA Polymerases. -The preparation of a novel phosphoramidite monomer based on thyminyl acetic acid coupled to a secondary nitrogen of 2-(2-amino-ethylamino)ethanol (III) is described. This monomer can
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