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ChemInform Abstract: Synthesis of New Bisphosphonate and Bisphosphonic Acid Derivatives and Heterocyclic and Dialkylcarbamoyl Oxazolone Derivatives with Anticancer and Antischistosomal Activity.

โœ Scribed by Leila S. Boulos; Ewies F. Ewies; Amin F. M. Fahmy

Publisher
John Wiley and Sons
Year
2012
Weight
33 KB
Volume
43
Category
Article
ISSN
0931-7597

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N-(9H-Xanthen-9-yl)succinimide (1) is prepared by the reaction of xanthene with N-bromosuccinimide. Hydrolysis of 1 with 5% NaOH yields 3-[(9H-xanthen-9-yl)inocarbonyl]propionic acid (3a). The corresponding methyl ester 3c is obtained from 3a by the action of diazomethane. The butanol derivative 4a