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ChemInform Abstract: Synthesis of New 5-Acetyl(arylmethyliden)-4-thiazolidones.

✍ Scribed by Svyatoslav V. Polovkovych; Andrii I. Karkhut; Natalia G. Marintsova; Volodymyr P. Novikov

Publisher
John Wiley and Sons
Year
2010
Weight
23 KB
Volume
41
Category
Article
ISSN
0931-7597

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## Abstract The synthesis of two diastereomers of the title compound involves the coupling of 5‐lithiated 2‐(1,1‐dimethoxyethyl)thiazole (VI) with a Weinreb amide (V) derived from gluconolacetone, followed by asymmetric reduction of the ketone functionality.