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ChemInform Abstract: Synthesis of N-Substituted 3-Oxo-17β-carboxamide-4-aza-5α-androstanes and the Tautomerism of 3-Oxo-4-aza-5-androstenes.

✍ Scribed by P. XIA; Z. YANG; Y. XIA; H. ZHANG; K. ZHANG; X. SUN; Y. CHEN; Y. ZHENG

Publisher
John Wiley and Sons
Year
2010
Weight
38 KB
Volume
29
Category
Article
ISSN
0931-7597

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The synthesis in eight steps of the title compound from the commercially available[2O-"C]pregnenolone 1 is described. ## The expected I-[4-methyl-3-oxo-4-aza-5a-androstane-17~-[14C]carbonyl]-1,3-diisopropylurea ([14C]FCE 26073) was obtained with a radiochemical purity higher than 97% and a specif