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ChemInform Abstract: Synthesis of N-Aryl-N′-Undecanoyl Thiourea Derivatives.

✍ Scribed by George Loloiu; Teodora Loloiu; Niculina Badicu; Daniela Gavriliu; Ovidiu Maior

Publisher: John Wiley and Sons
Year: 2010
Weight: 25 KB
Volume: 33
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.200249096

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Starting from amino(di)azines and 2-chloro-6-methyliso(thio)cyanate a series of aryl-substituted urea and thiourea derivatives was prepared and screened as potential antiepileptics. Among the new derivatives tested, only 2b and 3c exhibited adequate anticonvulsant effects, whereas 3d and 4d were fou