Synthesis of N-Aryl-N′-heteroaryl-Substi
✍
Gottfried Heinisch; Barbara Matuszczak; Dietmar Rakowitz; Boonyong Tantisira
📂
Article
📅
1997
🏛
John Wiley and Sons
🌐
English
⚖ 338 KB
👁 2 views
Starting from amino(di)azines and 2-chloro-6-methyliso(thio)cyanate a series of aryl-substituted urea and thiourea derivatives was prepared and screened as potential antiepileptics. Among the new derivatives tested, only 2b and 3c exhibited adequate anticonvulsant effects, whereas 3d and 4d were fou