ChemInform Abstract: Synthesis of Methyl 4-O-Methyl-β-D-ribo-hex-3-ulopyranoside-1-13C and Methyl 4-O-Methyl-β-D-ribo-hex-3-ulopyranoside-3-13C as Fragment Analogues of Oxidized Cellulose Units.
✍ Scribed by Karin Krainz; Andreas Hofinger; Thomas Dietz; Hans-Ulrich Suess; Antje Potthast; Thomas Rosenau
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 23 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Abstract
To ensure the synthetic approach to the labeled title compounds, the route is optimized with non‐labeled material according to the scheme.
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5-Dcoxy-J,2-O-isopropylidene-S-C-(methoxyphenylphosphinyl)-~-O-~~thyl-n-D-ribofuranose (4) was prepared from 1,2-0-isopropylidene-3-O-methyl-a-D-ribo-pentodialdo-1,4-furanose by an addition reaction with methyl phenylphosphinate, followed by deoxygenation of the terminal HO-$H-P group of the adduct
IZUMI TAKAI, YOSHIFUSA TACHIMORI, AZUMA YAMAMOTO, YOSHIHARU ISHIDO\*, AND (the late) ROKURO SUWH