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ChemInform Abstract: Synthesis of Linearly and Angularly Fused Indan-Based Constrained α-Amino Acid Derivatives.

✍ Scribed by Sambasivarao Kotha; Nimita Gopal Krishna; Shilpi Misra; Priti Khedkar


Publisher
John Wiley and Sons
Year
2012
Weight
38 KB
Volume
43
Category
Article
ISSN
0931-7597

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Synthesis of Constrained α-Amino Acid Derivatives via Enyne Metathesis Reaction. -Ring-closing metathesis of the enyne (VI), prepared following an optimized approach, in the presence of Grubb's catalyst gives the vinylcyclopentene (VII). The latter undergoes Diels-Alder reaction with the appropriat