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ChemInform Abstract: Synthesis of Highly Substituted Pyrrolidines via Palladium-Catalyzed Cyclization of 5-Vinyloxazolidinones and Activated Alkenes.

✍ Scribed by Julian G. Knight; Paul A. Stoker; Kirill Tchabanenko; Simon J. Harwood; Kenneth W. M. Lawrie

Publisher
John Wiley and Sons
Year
2008
Weight
34 KB
Volume
39
Category
Article
ISSN
0931-7597

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Serotonergic Activity. -A series of novel 3-arylpyrrolidines, e.g. (IV), (VI), and (VIII), is prepared for structure-activity relationship investigations of CNS stabilizers. The meta substitution at the aromatic ring seems to be necessary for good receptor binding activity. The use of monodentate ph