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ChemInform Abstract: Synthesis of Functionalized 2,3-Dihydroisoxazoles by Domino Reactions in Water and Unexpected Ring-Opening Reactions of 2,3-Dihydroisoxazoles.

โœ Scribed by Ping Li; Bo-Tao Teng; Fa-Gen Jin; Xin-Sheng Li; Wei-Dong Zhu; Jian-Wu Xie


Book ID
112045117
Publisher
John Wiley and Sons
Year
2012
Weight
44 KB
Volume
43
Category
Article
ISSN
0931-7597

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## Abstract Ringโ€opening reactions of 3โ€arylaziridineโ€2โ€carboxylic esters with various nucleophiles are described. Racemic methyl 3โ€(4โ€methoxyphenyl)โ€, 3โ€phenylโ€ and 3โ€(4โ€nitrophenyl)aziridineโ€2โ€carboxylate (1a, 1b and 1c, respectively) were selected as substrates. In the absence of acid, no ring o