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ChemInform Abstract: Synthesis of Five Nevirapine Metabolites.

โœ Scribed by Karl G. Grozinger; Denis P. Byrne; Laurence J. Nummy; Michael D. Ridges; Annette Salvagno

Publisher
John Wiley and Sons
Year
2000
Weight
35 KB
Volume
31
Category
Article
ISSN
0931-7597

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โœฆ Synopsis

Abstract

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a โ€œFull Textโ€ option. The original article is trackable via the โ€œReferencesโ€ option.

๐Ÿ“œ SIMILAR VOLUMES

Synthesis of five nevirapine metabolites
Synthesis of five nevirapine metabolites
โœ Karl G. Grozinger; Denis P. Byrne; Laurence J. Nummy; Michael D. Ridges; Annette ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› Journal of Heterocyclic Chemistry ๐ŸŒ English โš– 780 KB

## Abstract Nevirapine (**1**) is a nonโ€nucleoside reverse transcriptase inhibitor marketed for HIV treatment by Boehringer Ingelheim as Viramuneยฎ since 1996. __In vitro__ studies of nevirapine biotransformation using human liver microsomes demonstrated the formation of five major metabolites. This