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ChemInform Abstract: Synthesis of Dihydrothiophenes or Spirocyclic Compounds by Domino Reactions of 1,3-Thiazolidinedione.

✍ Scribed by Jing Sun; Li-Li Zhang; Er-Yan Xia; Chao-Guo Yan

Publisher
John Wiley and Sons
Year
2009
Weight
29 KB
Volume
40
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Diastereoselective
ChemInform Abstract: Diastereoselective Synthesis of trans-2,3-Dihydrothiophenes via Multicomponent Reactions of Pivaloylacetonitrile, Aldehyde, Amine, and Thiazolidinedione.
✍ Jing Sun; Qun Wu; Er-Yan Xiao; Chao-Guo Yan πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons βš– 27 KB

## Abstract A four‐component reaction of thiazoline‐2,4‐dione, aromatic aldehydes, cyclic secondary amines, and pivaloylacetonitrile yields the target compounds with excellent diastereoselectivity.