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ChemInform Abstract: Diastereoselective Synthesis of trans-2,3-Dihydrothiophenes via Multicomponent Reactions of Pivaloylacetonitrile, Aldehyde, Amine, and Thiazolidinedione.

✍ Scribed by Jing Sun; Qun Wu; Er-Yan Xiao; Chao-Guo Yan

Publisher
John Wiley and Sons
Year
2011
Weight
27 KB
Volume
42
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

A four‐component reaction of thiazoline‐2,4‐dione, aromatic aldehydes, cyclic secondary amines, and pivaloylacetonitrile yields the target compounds with excellent diastereoselectivity.

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