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ChemInform Abstract: Synthesis of C-Ribosyl Imidazo[2,1-f][1,2,4]triazines as Inhibitors of Adenosine and AMP Deaminases.

✍ Scribed by Philip J. Dudfield; Van-Duc Le; Stephen D. Lindell; Charles W. Rees

Publisher: John Wiley and Sons
Year: 2010
Weight: 34 KB
Volume: 31
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.200007199

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## Synthesis, Diastereoisomeric Resolution and Biological Activity of 1-(2-Hydroxy-3-nonyl)-1,2,4triazole-3-carboxamide. -The synthesis and diastereomeric resolution of the title carboxamides, which are good inhibitors of adenosine deaminase, is described. The erythro isomer (VIII) proves to be m

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