ChemInform Abstract: Synthesis of Bridged Analogues of Epibatidine. 3-Chloro-5,7,8,9,9a,10-hexahydro-7,10-methanopyrrolo [1,2-b]-2,6-naphthyridine and 2-Chloro-5,5a,6,7,8,10-hexahydro-5,8-methanopyrrolo [2,1-b]-1,7-naphthyridine.
β Scribed by Lawrence E. Brieaddy; S. Wayne Mascarella; Hernan A. Navarro; Robert N. Atkinson; M. I. Damaj; Billy R. Martin; F. Ivy Carroll
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 30 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
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π SIMILAR VOLUMES
## Synthesis of 2,4- 6,7,8,9,9methanopyrimido[4,azocine. -Optimization of direct annulation of triaminopyrimidine (I) with cyclohexenone (II) is achieved using acetic acid as solvent in a screw-capped pressure tube that is heated at 120 β’ C for 18 hours. Compound (VII) as prototype, its derivative