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ChemInform Abstract: Synthesis of Bicyclic Ketals Related to Zaragozic Acid by a Novel Photoannulation.

✍ Scribed by K. D. FREEMAN-COOK; R. L. HALCOMB


Book ID
112038619
Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
27
Category
Article
ISSN
0931-7597

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Studies Towards the Synthesis of the Zaragozic Acids: A Novel Epoxide Cyclization Approach to the Formation of the Bicyclic Acetal Core. -Model studies towards the synthesis of the bicyclic core of zaragozic acid are reported. The strategy is based on an epoxide cyclization reaction. Thus, treatmen

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Model studies towards the bicyclic acetal core 1 of the zaragozic acids, based on the epoxide cyclisation reaction 4 ---) 3, are described. Epoxide 14 provides the desired bicyclic acetal skeleton 16, while epoxide 27 leads through 28 to an isomeric acetal 30.