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Studies towards the synthesis of the zaragozic acids: A novel epoxide cyclisation approach to the formation of the bicyclic acetal core

✍ Scribed by Ian Paterson; Klaus Feßner; M.Raymond V Finlay; Mark F Jacobs

Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
253 KB
Volume
37
Category
Article
ISSN
0040-4039

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✦ Synopsis

Model studies towards the bicyclic acetal core 1 of the zaragozic acids, based on the epoxide cyclisation reaction 4 ---) 3, are described. Epoxide 14 provides the desired bicyclic acetal skeleton 16, while epoxide 27 leads through 28 to an isomeric acetal 30.

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