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ChemInform Abstract: Synthesis of a Simple Representative of Trinitrothiolene 1,1-Dioxides.

โœ Scribed by I. E. EFREMOVA; V. M. BERESTOVITSKAYA; L. V. LAPSHINA; A. V. FEL'GENDLER; N. B. NEPOMNYASHCHAYA


Publisher
John Wiley and Sons
Year
2010
Weight
31 KB
Volume
29
Category
Article
ISSN
0931-7597

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ChemInform Abstract: A Synthesis of 4-Th
โœ K.-S. YEUNG; N. A. MEANWELL ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 33 KB

A Synthesis of 4-Thiomethylbenzisothiazolone-1,1-dioxide Using HDPT. -The title compounds (V), required for pharmaceutical studies, are efficiently prepared starting with regioselective benzylic bromination of the corresponding dioxides (I). Coupling of the resulting benzyl bromides with HDPT (III)