𝔖 Bobbio Scriptorium
✦   LIBER   ✦

ChemInform Abstract: Synthesis of a Series of Sulfinic Acid Analogues of GABA and Evaluation of Their GABAB Receptor Affinities.

✍ Scribed by Nicholas I. Carruthers; ET AL. ET AL.

Publisher
John Wiley and Sons
Year
2010
Weight
34 KB
Volume
30
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.

✦ Synopsis

Synthesis of a Series of Sulfinic Acid Analogues of GABA and Evaluation of Their GABA B Receptor Affinities. -The replacement of the carboxyl group by a sulfinyl moiety in GABA analogues is investigated. The synthesis follows a similar procedure as shown for derivative (XII). Introduction of an additional carbon atom, cf. (IV), retains good GABA binding affinity, whereas the sulfinic moiety does not increase the desired activity. -(CARRUTHERS, NICHOLAS I.;

πŸ“œ SIMILAR VOLUMES

ChemInform Abstract: Synthesis and Recep
ChemInform Abstract: Synthesis and Receptor Binding Affinity of Conformationally Restricted Retinoic Acid Analogues.
✍ M. F. WONG; J. J. REPA; M. CLAGETT-DAME; R. W. JUN. CURLEY πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 34 KB πŸ‘ 1 views

Synthesis and Receptor Binding Affinity of Conformationally Restricted Retinoic Acid Analogues. -Efforts to synthesize two conformationally restricted retinoids utilizing a cyclopropyl ring as bioisostere for the C9-C10 double bond are described. The attempted synthesis of the cisisomer leads mainl

ChemInform Abstract: Synthesis of the Ξ³-
ChemInform Abstract: Synthesis of the Ξ³-Sulfinic Acid and Ξ³-Nitro Analogues of 5-Deazatetrahydrofolic Acid.
✍ Ronald A. Forsch; Joel E. Wright; Andre Rosowsky πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 29 KB

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v

ChemInform Abstract: Synthesis of Aristo
ChemInform Abstract: Synthesis of Aristolactam Analogues and Evaluation of Their Antitumor Activity.
✍ Young Lok Choi; Joa Kyum Kim; Sang-Un Choi; Yong-Ki Min; Myung-Ae Bae; Bum Tae K πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons βš– 31 KB πŸ‘ 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v

ChemInform Abstract: Synthesis of a New
ChemInform Abstract: Synthesis of a New Homologous Series of p-Chlorophenyl Alcohol Amides, Their Anticonvulsant Activity and Their Testing as Potential GABAB Receptor Antagonists.
✍ S. E. MEZA-TOLEDO; E. JUAREZ-CARVAJAL; G. CARVAJAL-SANDOVAL πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 31 KB πŸ‘ 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v