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ChemInform Abstract: Synthesis of a 3-Arylisoquinoline Alkaloid, Decumbenine B.

✍ Scribed by Yasuhiro Wada; Naoto Nishida; Nobuhito Kurono; Takashi Ohkuma; Kazuhiko Orito

Book ID
102018706
Publisher
John Wiley and Sons
Year
2008
Weight
12 KB
Volume
39
Category
Article
ISSN
0931-7597

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Synthesis of a 3-Arylisoquinoline Alkalo
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✍ Yasuhiro Wada; Naoto Nishida; Nobuhito Kurono; Takashi Ohkuma; Kazuhiko Orito πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 174 KB

## Abstract The synthesis of a 3‐arylisoquinoline alkaloid, decumbenine B, was accomplished in a reaction sequence based on the formation of an indolizine ring {dibenz[__a__,__f__]indolizin‐5(7__H__)‐one} followed by its cleavage at the amide bond, starting with an interaction of 5,6‐(methylenediox

ChemInform Abstract: Synthesis and Biolo
ChemInform Abstract: Synthesis and Biological Evaluation of 3-Arylisoquinolines as Antitumor Agents.
✍ W.-J. CHO; M.-J. PARK; B.-H. CHUNG; C.-O. LEE πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 28 KB πŸ‘ 2 views

Synthesis and Biological Evaluation of 3-Arylisoquinolines as Antitumor Agents. -Among the newly synthesized 3-arylisoquinolines the unsubstituted derivatives (I) and (III) show the best in vitro antitumor activity. The activity of the lead compound SKMEL-2 is not achieved, so that further function