✦ LIBER ✦

ChemInform Abstract: Synthesis and Biological Evaluation of 3-Arylisoquinolines as Antitumor Agents.

✍ Scribed by W.-J. CHO; M.-J. PARK; B.-H. CHUNG; C.-O. LEE

Publisher: John Wiley and Sons
Year: 2010
Weight: 28 KB
Volume: 29
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199818162

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✦ Synopsis

Synthesis and Biological Evaluation of 3-Arylisoquinolines as Antitumor Agents.

-Among the newly synthesized 3-arylisoquinolines the unsubstituted derivatives (I) and (III) show the best in vitro antitumor activity. The activity of the lead compound SKMEL-2 is not achieved, so that further functionalities will be investigated. -(CHO, W.-

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