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ChemInform Abstract: Synthesis of 6-Substituted 1-Deazapurine 2′-Deoxyribonucleosides.

✍ Scribed by T. WENZEL; F. SEELA


Book ID
112031305
Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
27
Category
Article
ISSN
0931-7597

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Synthesis of 6-Substituted 1-Deazapurine
✍ Thomas Wenzel; Frank Seela 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 German ⚖ 590 KB

## Abstract The synthesis of 6‐substituted 1‐deazapurine 2′‐deoxyribonucleosides is described. Glycosylation of the 1‐deazapurine (imidazo[4,5‐__b__]pyridine) anions with the α‐D‐halogenose 5 gives stereoselectively __N__^7^‐ and __N__^9^‐ regioisomers. ^1^H‐NMR NOE and ^13^C‐NMR spectroscopy are u