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ChemInform Abstract: Synthesis of 5′-C-Hydroxyalkylthymidines and Their Incorporation into Oligodeoxynucleotides.

✍ Scribed by G. WANG; P. J. MIDDLETON; Y.-Z. AN


Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
28
Category
Article
ISSN
0931-7597

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✦ Synopsis


Synthesis of 5'-C-Hydroxyalkylthymidines and Their Incorporation into Oligodeoxynucleotides.

-Starting from known thymidine derivatives, title compounds (VII), (IX), and (XI) are prepared. Incorporation may be achieved by conversion to side-chain acetylated phosphoramidites. -(WANG,


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