ChemInform Abstract: Synthesis of (-)-3-
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Michael Mueller; Rolf Mueller; Tin-Wein Yu; Heinz G. Floss
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Article
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2010
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John Wiley and Sons
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Synthesis of (-)-3-Amino-3-deoxyquinic Acid. -The title acid (X) is prepared in nine steps from quinic acid (I) in 14% overall yield. Its importance for the biosynthesis of 3-amino-5-hydroxybenzoic acid, the precursor of mC 7 N-units in ansamycin and mitomycin antibiotics is discussed. -