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ChemInform Abstract: Synthesis of 3-Carboxylic Derivatives of 1,5-Benzodiazepines.

โœ Scribed by O. Mansour; B. Szymonski; F. Thomasson; J. M. Morand; M. Cussac


Publisher
John Wiley and Sons
Year
2010
Weight
31 KB
Volume
32
Category
Article
ISSN
0931-7597

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ChemInform Abstract: A Convenient Synthe
โœ A. PIPAUD; R. ROCHER; J. CHENAULT ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 32 KB

Benzodiazepin-1-one-2-carboxylic Acid and a 3-Cyanoindole. -Key step of the described synthesis is the intramolecular cyclization of the precursors (IV) and (VI) in Ph 2 O. In the latter case compound (VII), which is formed via elimination of HNCO, is isolated as a side product. -(