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ChemInform Abstract: Synthesis of 3′-Aroyl-4′-hydroxyspiro[indole-3,2′-furan]-2,5′(1H)-diones.

✍ Scribed by V. L. Gein; E. B. Levandovskaya; V. N. Vichegjanina


Publisher
John Wiley and Sons
Year
2011
Weight
28 KB
Volume
42
Category
Article
ISSN
0931-7597

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Synthesis of 5H-Pyrazino(2,3-b)indoles from Indole-2,3-dione Derivatives. -The reaction of the N-acetylisatins (I) with ethylenediamine yields the products (III). After dehydrogenation these compounds and their analogues (IV) after deacetylation are cyclized by heating to the title products (VI). N