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ChemInform Abstract: Synthesis of 2′,3′-Dideoxy-2′,3′-didehydro Nucleosides via a Serendipitous Route

✍ Scribed by Z. Guo; Y. S. Sanghvi; L. E. Brammer Jr.; T. Hudlicky


Publisher
John Wiley and Sons
Year
2010
Weight
25 KB
Volume
32
Category
Article
ISSN
0931-7597

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Abstract

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.


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Synthesis and Biological Evaluation of a Series of 2'-Fluorinated-2',3'-dideoxy-2',3'-didehydro-(L)-nucleosides. -A general method for the synthesis of both the cis-and trans-2'-vinylfluoro containing nucleosides is presented. Among the nucleosides prepared compound (XI) displays the best biologica