ChemInform Abstract: Synthesis of 2′,3′-Dideoxy-2′,3′-didehydro Nucleosides via a Serendipitous Route
✍ Scribed by Z. Guo; Y. S. Sanghvi; L. E. Brammer Jr.; T. Hudlicky
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 25 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Abstract
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Synthesis and Biological Evaluation of a Series of 2'-Fluorinated-2',3'-dideoxy-2',3'-didehydro-(L)-nucleosides. -A general method for the synthesis of both the cis-and trans-2'-vinylfluoro containing nucleosides is presented. Among the nucleosides prepared compound (XI) displays the best biologica