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ChemInform Abstract: Synthesis of 2,3-Aziridino-2,3-dideoxy-D-lyxono-γ-lactone 5- Phosphonate from D-Ribose, a New Member of the 2,3-Aziridino-γ- lactone Family of Synthons.

✍ Scribed by P. DAUBAN; B. HOFMANN; R. H. DODD


Publisher
John Wiley and Sons
Year
2010
Weight
33 KB
Volume
28
Category
Article
ISSN
0931-7597

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Syntheses of 2',3'-Dideoxy-D-C-nucleosides from γ-Lactone. -A versatile method for the synthesis of 2',3'-dideoxy-D-C-nucleosides such as (X)/(XI) and (XVII)/(XVIII) starting from γ-lactone (I) is presented. None of the target compounds shows significant activities against HBV and HIV as well as si