ChemInform Abstract: Synthesis of 2-Aryl-4H-pyrano[2,3-b]pyridin-4-ones by a One-Pot Deprotection—Cyclization Reaction.
✍ Scribed by Vladimir Khlebnikov; Kalpesh Patel; Xiaojian Zhou; M. Madhava Reddy; Zhuoyi Su; Fabrizio S. Chiacchia; Henrik C. Hansen
- Publisher
- John Wiley and Sons
- Year
- 2009
- Weight
- 47 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0931-7597
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## Abstract 2‐Aryl‐2,3‐dihydro‐4__H__‐pyran‐4‐ones were prepared in one step by cyclocondensation of 1,3‐diketone dianions with aldehydes. The use of HCl (10%) for the aqueous workup proved to be very important to avoid elimination reactions of the 5‐aryl‐5‐hydroxy 1,3‐diones formed as intermediate