ChemInform Abstract: Synthesis of 13C-Dilabeled 4-Coumaroylspermidines.

✍ Scribed by Herve Geneste; Manfred Hesse

• Book ID: 101875965
• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 26 KB
• Volume: 30
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199917258

✦ Synopsis

Synthesis of 13 C-Dilabeled 4-Coumaroylspermidines.

-Five title derivatives carrying one, two or three 4-coumaroyl groups are prepared in nine to eleven steps. The two 13 C-atoms are subsequently introduced using labeled potassium cyanide. The synthesis proceeds through stepwise construction of the polyamine backbone starting from 2-chloroethanol and including protection and deprotection steps of the amino functions. -(GENESTE, HERVE; HESSE,