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ChemInform Abstract: Synthesis of 1,2,4-Triazole and Thiazole Analogues of Ketoconazole.

โœ Scribed by L.-F. HUANG; J.-W. KIM; L. BAUER; G. DOSS


Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
28
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Synthesis of Benzot
โœ J. BOLOS; S. GUBERT; L. ANGLADA; A. SACRISTAN; J. A. ORTIZ ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 38 KB ๐Ÿ‘ 1 views

Synthesis of Benzothiophene Analogues of Ketoconazole and Itraconazole. -Benzothiophene analogues (VII) and (XV) of the orally active antifungal title agents are synthesized and subjected to preliminary pharmacological evaluation. The key heterocyclic system (III) is prepared by formation of the en