ChemInform Abstract: Synthesis of Benzot
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J. BOLOS; S. GUBERT; L. ANGLADA; A. SACRISTAN; J. A. ORTIZ
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Article
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2010
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John Wiley and Sons
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Synthesis of Benzothiophene Analogues of Ketoconazole and Itraconazole. -Benzothiophene analogues (VII) and (XV) of the orally active antifungal title agents are synthesized and subjected to preliminary pharmacological evaluation. The key heterocyclic system (III) is prepared by formation of the en