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ChemInform Abstract: Synthesis of 11-Bromo-9-methyl-6-methylene-3-methylthio-5,6,9,10-tetrahydro-8H- [1,2,4]triazolo[3′,4′:3,4]pyrazino[1,2-c]pyrimidine-8,10-dione from 4-Allyl-1- (3-methyl-2,4-dioxo-1,2,3,4-tetrahydro-6-pyrimidinylcarbonyl) thiosemicarbazide.

✍ Scribed by G. Myakushkene; P. Vainilavichyus

Publisher
John Wiley and Sons
Year
2010
Weight
31 KB
Volume
31
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

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✍ M. R. DEL GIUDICE; A. BORIONI; C. MUSTAZZA; F. GATTA 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 39 KB 👁 1 views

In order to prepare new tacrine-like compounds, the title compounds (VII), (X) and (XV) are synthesized. The synthetic pathway to (VII) represents a shorter and more suitable approach to prepare tacrine metabolites. An alternative route from (VIb) to compound (VIII), which exhibits very strong DNA b