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ChemInform Abstract: Synthesis of 1-Alkoxy-5-alkyluracils.

✍ Scribed by D.-K. KIM; G. KIM; J. LIM; K. H. KIM

Book ID
112029612
Publisher
John Wiley and Sons
Year
2010
Weight
27 KB
Volume
27
Category
Article
ISSN
0931-7597

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## Abstract Synthesis of 6‐substituted 1‐alkoxy‐5‐alkyluracils 2a‐c have been achieved from readily accessible 2‐alkyl‐3,3‐di(methylthio)acryloyl chlorides 4a,b in high overall yields. Treatment of 4a,b with silver cyanate followed by reaction of the resulting isocyanates 5a,b with an appropriate a