ChemInform Abstract: Synthesis and Structure—Activity Relationships of 3-Hydrazono-1H-2-indolinones with Antituberculosis Activity.

✍ Scribed by N. KARALI; N. TERZIOGLU; A. GUERSOY

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 31 KB
• Volume: 29
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199844123

✦ Synopsis

Synthesis and Structure-Activity Relationships of 3-Hydrazono-1H-2-indolinones with Antituberculosis Activity.

-Reaction of 3-thiosemicarbazonoindolinones (I) with 2-bromoacetophenones (II) provides 3-thiazolinylidenehydrazones (III) or isothiosemicarbazones (IV) in good yield. These new hydrazonoindolinone derivatives and a variety of previously described hydrazones are evaluated for their antituberculosis activity. -(KARALI, N.;