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ChemInform Abstract: Synthesis and Screening of Quinolone Antibiotic Isosteres.

โœ Scribed by Mohamed A. Shaban; Ossama M. Al Badry; Aliaa M. Kamal; Mohamed Abd el Wahap Abd El-Gawad


Publisher
John Wiley and Sons
Year
2009
Weight
26 KB
Volume
40
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Design and Synthesi
โœ A. O. GOLDRING; J. BALZARINI; I. H. GILBERT ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 32 KB ๐Ÿ‘ 2 views

Design and Synthesis of Bio-Isosteres of Thymidine Triphosphate. -First metabolic stable and lipophilic triphosphate isosteres are prepared and subsequent linked to nucleosides such as (VIII) and (IX) derived from pyrrole (VII). None of the products show surprisingly the desired anti-HIV activity.