ChemInform Abstract: Synthesis and Reactivity of Some Mannich Bases. Part 7. Synthesis of 3-(2-Dialkylaminoethyl)-1,2-benzisoxazoles.

✍ Scribed by Eugenia Comanita; Irina Popovici; Gheorghe Roman; Gilles Robertson; Bogdan Comanita

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 29 KB
• Volume: 30
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199952132

✦ Synopsis

Synthesis and Reactivity of Some Mannich Bases. Part 7. Synthesis of 3-(2-Dialkylaminoethyl)-1,2-benzisoxazoles.

-Acetylation of the oximes (I) and direct basic treatment of the resulting Mannich base oxime acetates (III) yields the 1,2-benzisoxazoles (IV), required as pharmaceutical agents. -(COMANITA, EUGENIA;