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ChemInform Abstract: Controlled Synthesis of Novel Dibenzene-1,2-diol Mannich Bases.

โœ Scribed by Marcus J. Caulfield; Tiziana Russo; David H. Solomon

Publisher
John Wiley and Sons
Year
2001
Weight
29 KB
Volume
32
Category
Article
ISSN
0931-7597

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Synthesis and Reactivity of Some Mannich Bases. Part 7. Synthesis of 3-(2-Dialkylaminoethyl)-1,2-benzisoxazoles. -Acetylation of the oximes (I) and direct basic treatment of the resulting Mannich base oxime acetates (III) yields the 1,2-benzisoxazoles (IV), required as pharmaceutical agents. -(COMA