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ChemInform Abstract: Synthesis and Photochemical Activity of Designed Enediynes.

โœ Scribed by Graham B. Jones; Justin M. Wright; Gary Plourde II; Ajay D. Purohit; Justin K. Wyatt; George Hynd; Farid Fouad


Publisher
John Wiley and Sons
Year
2001
Weight
33 KB
Volume
32
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Novel Heterocyclic
โœ K. TOSHIMA; K. OHISHI; M. TOMISHIMA; S. MATSUMURA ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 30 KB ๐Ÿ‘ 1 views

Novel Heterocyclic Enediynes. Molecular Design, Chemical Synthesis and DNA Cleavage. -Novel 10-membered oxa-or azaenediynes such as (IV) and (IX) are prepared in short procedures from the known diynes (I) and (V). The azadiynes show effective DNA cleavage under both weakly basic and acidic conditio