ChemInform Abstract: Synthesis and Pharmacological Characterization of a Conformationally Restrained Series of Indole-2-carboxylates [cf. (VI)] as in vivo Potent Glycine Antagonists.

ChemInform Abstract: Synthesis and Biolo

ChemInform Abstract: Synthesis and Biological Evaluation of a Series of Quinazoline-2- carboxylic Acids and Quinazoline-2,4-diones as Glycine-NMDA Antagonists: A Pharmacophore Model Based Approach.

✍ V. COLOTTA; D. CATARZI; F. VARANO; L. CECCHI; G. FILACCHIONI; A. GALLI; C. COSTA 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 31 KB

Synthesis and Biological Evaluation of a Series of Quinazoline-2carboxylic Acids and Quinazoline-2,4-diones as Glycine-NMDA Antagonists: A Pharmacophore Model Based Approach. -Although the compounds studied contain all features required by the antagonist pharmacophore model, they only show poor aff