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ChemInform Abstract: Synthesis and Pharmacological Activity of Derivatives of myo-Inositol with Nicotinic and γ-Aminobutyric Acids.

✍ Scribed by I. N. GRACHEVA; E. M. OREKHOVA; V. M. KOPELEVICH; I. N. TYURENKOV; B. A. KLESHCHITSKII; V. I. SHVETS

Book ID
112041424
Publisher
John Wiley and Sons
Year
2010
Weight
35 KB
Volume
27
Category
Article
ISSN
0931-7597

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Synthesis and Pharmacological Activity of Hetaroylpyruvic Acids and Their Derivatives. -Claisen condensation of acetylheterocycles (I) with diethyl oxalate (II) affords hetaroylpyruvic acids (III) which contain a fully enolized α-carbonyl group. On reaction with hydrazines, they undergo cycloconden