ChemInform Abstract: Synthesis and Ligand Binding Studies of 4′-Iodobenzoyl Esters of Tropanes and Piperidines at the Dopamine Transporter.
✍ Scribed by S. SINGH; G. P. BASMADJIAN; K. S. AVOR; B. POUW; T. W. SEALE
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 32 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0931-7597
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Synthesis of the Isomers of (1R)-3-(Phenylthio)tropane-2-carboxylic Acid Methyl Ester. A New Class of Ligands for the Dopamine Transporter. -The syntheses of all four diastereomers of the title compound is described. The isomer (IV) is the most potent at the cocaine binding site of the dopamine tra
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